The proposed concept would be a reissue of the Division of the Division of AIDS Research (DAR) program announcements that support Center Core grants (P30) for HIV/AIDS Research Centers (ARCs) and Developmental Centers (D-ARCs). The goal of the initiative is to fund Centers that provide infrastructure for the development of high impact science in HIV/AIDS and mental health that is relevant to the NIMH mission. The intent of D-ARC support is that the Core activities will allow the D-ARC to compete successfully for a full ARC after the D-ARC award period.