The purpose of this article was to systematically review the play therapy literature examining the effectiveness of child-centered play therapy with the autism spectrum disorder (ASD) population. Child-centered play therapy is shown to be an evidence-based, effective intervention for children; however, a systematic review of child-centered play therapy as an intervention with the ASD population has yet to be conducted. Even though results of the literature review show that child-centered play therapy is promising in increasing social and emotional behaviors of children with ASD, more research is needed to determine whether child-centered play therapy is an efficacious intervention with children with autism spectrum disorder. (PsycINFO Database Record (c) 2018 APA, all rights reserved)